Publications

Murepavadin activity tested against contemporary (2016-2017) clinical isolates of extensively drug-resistant (XDR) Pseudomonas aeruginosa. Lead author: HS Sader, presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2018, Madrid, Spain
# P1661

Activity of telavancin against a global collection of multidrug-resistant Gram-positive isolates and ceftaroline-nonsusceptible Staphylococcus aureus (2015-2017). Lead author: LR Duncan, presented at the 28th European Congress of Clinical Microbiology and Infections Diseases (ECCMID) 2018, April 21-24, Madrid, Spain
# P1808

Current in vitro analysis of tedizolid activity against Gram-positive clinical isolates causing bloodstream infections in Europe and surrounding areas (2014-2017). Lead author: RE Mendes, presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2018, April 21-24, Madrid, Spain
# P1806

The application of in vitro surveillance data for antibacterial dose selection. by Flamm RK, Sader HS, Castanheira M and Jones RN published in Curr Opin Pharmacol 2017; 36:130-138

In vitro activity of the novel lactone ketolide nafithromycin (WCK 4873) when tested against contemporary clinical bacteria from a global surveillance program. by Flamm RK, Rhomberg PR and Sader HS published in Antimicrob. Agents Chemother. 2017; 61 (12): e01230

Activity of Tedizolid against Gram-Positive Clinical Isolates Causing Nosocomial- and Community-Acquired Infections in United States Hospitals (2014-2016), Lead author: Mendes RE, presented at IDWeek 2017, October 4-8, San Diego, CA, USA
Poster #1215

Ceftobiprole Activity When Tested against Contemporary Bacteria Causing Bloodstream Infections in the US (2016), Lead author: Flamm RK, presented at IDWeek 2017, October 4-8, San Diego, CA, USA
Poster #1205

In vitro Evaluation of Delafloxacin Activity When Tested against Contemporary Community-Acquired Bacterial Respiratory Tract Infection Isolates (2014-2106): Results from the SENTRY Antimicrobial Surveillance Program, Lead author: Shortridge D, presented at IDWeek 2017, October 4-8, San Diego, CA, USA
Poster #1208

Cefepime-Zidebactam (WCK 5222) Activity Tested against Gram-Negative Organisms Causing Bloodstream Infections Worldwide, Lead author: Sader HS, presented at IDWeek 2017, October 4-8, San Diego, CA, USA
Poster #1226

In Vitro Activity of Omadacycline and Comparator Compounds against Gram-Positive Isolates Collected in the US During 2016 as Part of a Global Surveillance Program, Lead author: Huband MD, presented at IDWeek 2017, October 4-8, San Diego, CA, USA
Poster #1223

Broad In Vitro Activity Analysis of Tedizolid Compared with Other Agents against a Global Collection of Gram-Positive Isolates Causing Bloodstream Infections (2014-2016), Lead author: Mendes RE, presented at IDWeek 2017, October 4-8, San Diego, CA, USA
Poster #1210

Sustained In Vitro Activity of Linezolid and Evolving Resistance Mechanisms: Summary of the Zyvox^® Annual Appraisal of Potency and Spectrum Program for 2016, Lead author: Mendes RE, presented at IDWeek 2017, October 4-8, San Diego, CA, USA
Poster #329

Regional Analysis of Resistance Phenotypes among Staphylococcus aureus Causing Infections in US Census Divisions: Telavancin Activity against Resistant Pathogens (2014-2016), Lead author: Duncan LR, presented at IDWeek 2017, October 4-8, San Diego, CA, USA
Poster #333

Telavancin activity in vitro tested against a worldwide collection of gram-positive clinical isolates (2014). by Duncan LR, Sader HS, Smart JI, Flamm RK and Mendes RE published in J. Glob. Antimicrob. Resist.2017; 10: 271-276

Activity of dalbavancin tested against gram-positive clinical isolates causing skin and skin-structure infections in paediatric patients from US hospitals (2014 – 2015). by Pfaller MA, Mendes RE, Sader HS, Castanheira M and Flamm RK published in J. Glob. Antimicrob. Resist. 2017; 11: 4-7

In vitro activity of telavancin against clinically important gram-positive pathogens from 69 U.S. medical centers (2015): Potency analysis by U.S. census divisions. by Pfaller MA, Sader HS, Flamm RK, Castanheira M, Smart JI and Mendes RE published in Microb. Drug Resist., 2017; 23 (6): 718-726

In vitro activity of linezolid against clinically important gram-positive cocci in the United States: A 5-year summary of in vitro activity and resistance mechanisms from the LEADER Surveillance Program (2011-2015). by Pfaller MA, Mendes RE, Streit JM, Hogan PA and Flamm RK published in Antimicrob. Agents Chemother. 2017; 61 (7): e00609

In vitro activity of delafloxacin and microbiological response against fluoroquinolone susceptible and non-susceptible S. aureus isolates from two Phase 3 Studies of acute bacterial skin and skin structure infections (ABSSSI). by McCurdy S, Lawrence L, Quintas M, Woosley L, Flamm R, Tseng C and Cammarata S published in Antimicrob. Agents Chemother. 2017; 61 (9): e007722017

Gepotidacin (GSK2140944) in vitro activity against Gram-positive and Gram-negative bacteria. by Flamm RK, Farrell DJ, Rhomberg PR, Scangarella-Oman NE and Sader HS published in Antimicrob. Agents Chemother. 2017; 61 (7): e00468-17

Ceftaroline activity tested against bacterial isolates causing community-acquired respiratory tract infections and skin and skin structure infections in pediatric patients from United States hospitals: 2012-2014. by Pfaller MA, Mendes RE, Castanheira M, Flamm RK, Jones RN and Sader HS published in Pediatr. Infect. Dis. J. 2017; 36 (5): 486-491

Prevalence of macrolide-lincosamide resistance and multidrug resistance phenotypes in streptococcal isolates causing infections in European hospitals: Evaluation of the in vitro activity of oritavancin and comparator agents. by Mendes RE, Castanheira M, Farrell DJ, Flamm RK, Sader HS and Jones RN published in J. Glob. Antimicrob. Resist. 2017; 8: 28-32

Impact of defined cell envelope mutations in Escherichia coli on the in vitro antibacterial activity of avibactam/beta-lactam combinations. by McLeod SM, Patey SA, Huband MD and Nichols WW published in Int. J. Antimicrob. Agents. 2017; 49 (4): 437-442

Effect of susceptibility testing conditions on the in vitro antibacterial activity of ETX0914. by Giacobbe RA, Huband MD, deJonge BL and Bradford PA published in Diag. Microbio. Infect. Dis. 2017; 87 (2): 139-142

In vitro activity of gepotidacin (GSK2140944) against Neisseria gonorrhoeae. by Farrell DJ, Sader HS, Rhomberg PR, Scangarella-Oman NE and Flamm RK published in Antimicrob. Agents Chemother. 2017; 61 (3): e02047

In vitro activity of lefamulin tested against Streptococcus pneumoniae with defined serotypes, including multidrug-resistant isolates causing lower respiratory tract infections in the United States. by Mendes RE, Farrell DJ, Flamm RK, Talbot GH, Ivezic-Schoenfeld Z, Paukner S and Sader HS published in Antimicrob. Agents. Chemother. 2016; 60 (7): 4407-4411

Longitudinal (2001-14) analysis of enterococci and VRE causing invasive infections in European and US hospitals, including a contemporary (2010-13) analysis of oritavancin in vitro potency. by Mendes RE, Castanheira M, Farrell DJ, Flamm RK, Sader HS and Jones RN published in J. Antimicrob. Chemother. 2016; 71 (12): 3453-3458

In vitro activity of dalbavancin against multidrug-resistant Staphylococcus aureus and streptococci from patients with documented infections in Europe and surrounding regions (2011-2013). by Huband MD, Castanheira M, Farrell DJ, Flamm RK, Jones RN, Sader HS and Mendes RE published in Int. J. Antimicrob. Agents. 2016; 47 (6): 495-499

In vitro activity of delafloxacin tested against isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. by Flamm RK, Rhomberg PR, Huband MD and Farrell DJ published in Antimicrob. Agents Chemother. 2016; 60 (10): 6381-6385

In vitro spectrum of pexiganan activity; bactericidal action and resistance selection tested against pathogens with elevated MIC values to topical agents. by Flamm RK, Rhomberg PR, Farrell DJ and Jones RN published in Diagn. Microbiol. Infect. Dis. 2016; 86 (1): 66-69

Minocycline activity tested against Acinetobacter baumannii complex, Stenotrophomonas maltophilia, and Burkholderia cepacia species complex isolates from a global surveillance program (2013). by Flamm RK, Castanheira M, Streit JM and Jones RN published in Diagn. Microbiol. Infect. Dis. 2016; 85 (3): 352-355

Telavancin activity tested against a collection of Staphylococcus aureus isolates causing pneumonia in hospitalized patients in the United States (2013-2014). by Duncan LR, Smart JI, Flamm RK, Sader HS, Jones RN and Mendes RE published in Diagn. Microbiol. Infect. Dis. 2016; 86 (3): 300-302

Oritavancin in vitro activity against contemporary Staphylococcus aureus isolates responsible for invasive community- and healthcare-associated infections among patients in the USA (2013-2014). by Duncan LR, Sader HS, Flamm RK, Jones RN and Mendes RE published in Diagn. Microbiol. Infect. Dis. 2016; 86 (3): 303-306

In Vitro Activity of WCK 4282 (High-Dose Cefepime-Tazobactam) Against Resistant Subsets of Enterobacteriaceae Collected Worldwide (2014), Lead author: Sader HS, presented at 26th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 9-12, 2016, Amsterdam, Netherlands

In vitro activity of ceftazidime-avibactam against contemporary Pseudomonas aeruginosa isolates from United States medical centers by Census region (2014). by Huband MD, Castanheira M, Flamm RK, Farrell DJ, Jones RN and Sader HS. published in Antimicrob. Agents. Chemother. 2016; 60 (4): 2537-2541

In vitro activity of ceftazidime/avibactam against Gram-negative pathogens isolated from pneumonia in hospitalised patients, including ventilated patients. by Flamm RK, Nichols WW, Sader HS, Farrell DJ and Jones RN published in Int. J. Antimicrob. Agents. 2016; 47 (3): 235-242

In vitro antimicrobial activity of S-649266, a catechol-substituted siderophore cephalosporin, when tested against non-fermenting Gram-negative bacteria. by Ito A, Kohira N, Bouchillon SK, West J, Rittenhouse S, Sader HS, Rhomberg PR, Jones RN, Yoshizawa H, Nakamura R, Tsuji M and Yamano Y published in J. Antimicrob. Chemother. 2016; 71 (3): 670-677

In vitro activity of ceftolozane-tazobactam against anaerobic organisms identified during the ASPECT-cIAI study. by Armstrong ES, Farrell DJ, Palchak M and Steenbergen JN published in Antimicrob. Agents. Chemother. 2016; 60 (1): 666-668

In Vitro Activity of Delafloxacin Tested Against Streptococcus pneumoniae, Haemophilus influenza, and Moraxella catarrhalis, Lead author: Flamm RK, presented at 55th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 17-21,2015, San Diego, CA

Activity of Lefamulin, an Pleuromutilin Derivative, against S. aureus Strains with Decreased Susceptibility to Vancomycin, Lead author: Sader HS, presented at 55th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 17-21,2015, San Diego, CA

Solithromycin MIC and Disk Diffusion Quality Control Ranges, a CLSI Multi-Laboratory M23-A3 Study Design, Lead author: Ross JE, presented at 55th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 17-21,2015, San Diego, CA

Performance of BD MAX™ StaphSR against S. aureus Clinical Isolates from the 9 USA Census Regions, Lead author: Mendes RE, presented at 55th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 17-21,2015, San Diego, CA

Debio 1452 MIC QC Range with S. aureus ATCC 29213 Using a Multi-laboratory Study Design, Lead author: Flamm RK, presented at 25th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 25-29, 2015, Copenhagen, Denmark

Accuracy of Predicting Oritavancin Susceptibility using Vancomycin Surrogate Susceptibility Testing of GP from EU, Lead author: Jones RN, presented at 25th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 25-29, 2015, Copenhagen, Denmark

Antimicrobial potency of lefamulin (BC-3781) tested against S. pneumoniae with defined serotypes, including MDR isolates causing lower RTI in the USA, Lead author: Mendes RE, presented at 25th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 25-29, 2015, Copenhagen, Denmark

In vitro activity of RX-P873 against Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii. by Flamm RK, Rhomberg PR, Jones RN and Farrell DJ published in Antimicrob. Agents Chemother. 2015; 59 (4): 2280-2285

Arbekacin activity against contemporary clinical bacteria isolated from patients hospitalized with pneumonia. by Sader HS, Rhomberg PR, Farrell DJ and Jones RN published in Antimicrob. Agents. Chemother. 2015; 59 (6): 3263-3270

In vitro activity of a Hos2 deacetylase inhibitor, MGCD290, in combination with echinocandins against echinocandin-resistant Candida species. by Pfaller MA, Rhomberg PR, Messer SA and Castanheira M published in Diagn. Microbiol. Infect. Dis. 2015; 81 (4): 259-263

Update on the linezolid in vitro activity through the Zyvox® Annual Appraisal of Potency and Spectrum Program (2013). by Mendes RE, Hogan PA, Streit JM, Jones RN and Flamm RK published in Antimicrob. Agents Chemother. 2015; 59 (4): 2454-2457

Update of the telavancin activity in vitro tested against a worldwide collection of Gram-positive clinical isolates (2013), when applying the revised susceptibility testing method. by Mendes RE, Farrell DJ, Sader HS, Streit JM and Jones RN published in Diagn. Microbiol. Infect. Dis. 2015; 81 (4): 275-279

Use of in vitro vancomycin testing results to predict susceptibility to oritavancin, a new long-acting lipoglycopeptide. by Jones RN, Turnidge JD, Moeck G, Arhin FF and Mendes RE published in Antimicrob. Agents Chemother. 2015; 59 (4): 2405-2409,