Filter by Category: Molecular Studies

Simultaneous emergence of multidrug-resistant Candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses.

Simultaneous emergence of multidrug-resistant Candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses. by Lockhart SR, Etienne KA, Vallabhaneni S, Farooqi J, Chowdhary A, Govender NP, Colombo AL, Calvo B, Cuomo CA, Desjardins CA, Berkow EL, Castanheira M, Magobo RE, Jabeen K, Asghar RJ, Meis JF, Jackson B, Chiller T and Litvintseva AP published in Clin. Infect. Dis. 2017; 64 (2): 134-140

Empyema thoracis caused by an optrA-positive and linezolid-intermediate Enterococcus faecalis strain.

Empyema thoracis caused by an optrA-positive and linezolid-intermediate Enterococcus faecalis strain. by Chien JY, Mendes RE, Deshpande LM and Hsueh PR published in J. Infect. 2017; 75 (2): 182-184

Low frequency of ceftazidime-avibactam resistance among Enterobacteriaceae isolates carrying blaKPC collected in U.S. hospitals from 2012 to 2015.

Low frequency of ceftazidime-avibactam resistance among Enterobacteriaceae isolates carrying blaKPC collected in U.S. hospitals from 2012 to 2015. by Castanheira M, Mendes RE and Sader HS published in Antimicrob. Agents Chemother. 2017; 61 (3): e02369

β-Lactamase characterization of Gram-negative pathogens recovered from patients enrolled in the phase 2 trials for ceftazidime-avibactam: clinical efficacies analyzed against subsets of molecularly characterized isolates.

β-Lactamase characterization of Gram-negative pathogens recovered from patients enrolled in the phase 2 trials for ceftazidime-avibactam: clinical efficacies analyzed against subsets of molecularly characterized isolates. by Mendes RE, Castanheira M, Gasink L, Stone GG, Nichols WW, Flamm RK and Jones RN published in Antimicrob. Agents. Chemother. 2016; 60 (3): 1328-1335

International evaluation of MIC distributions and epidemiological cutoff value (ECV) definitions for fusarium species identified by molecular methods for the CLSI broth microdilution method.

International evaluation of MIC distributions and epidemiological cutoff value (ECV) definitions for fusarium species identified by molecular methods for the CLSI broth microdilution method. by Espinel-Ingroff A, Colombo AL, Cordoba S, Dufresne PJ, Fuller J, Ghannoum M, Gonzalez GM, Guarro J, Kidd SE, Meis JF, Melhem TM, Pelaez T, Pfaller MA, Szeszs MW, Takahaschi JP, Tortorano AM, Wiederhold NP and Turnidge J published in Antimicrob. Agents. Chemother. 2016; 60 (2): 1079-1084

Changes in the frequencies of β-lactamase genes among Enterobacteriaceae isolates in U.S. Hospitals, 2012 to 2014: Activity of ceftazidime-avibactam tested against β-lactamase-producing isolates.

Changes in the frequencies of β-lactamase genes among Enterobacteriaceae isolates in U.S. Hospitals, 2012 to 2014: Activity of ceftazidime-avibactam tested against β-lactamase-producing isolates. by Castanheira M, Mendes RE, Jones RN and Sader HS published in Antimicrob. Agents. Chemother. 2016; 60 (8): 4770-4777

Evolution of ceftaroline-resistant MRSA in a child with cystic fibrosis following repeated antibiotic exposure

Evolution of ceftaroline-resistant MRSA in a child with cystic fibrosis following repeated antibiotic exposure. by Cannavino CR, Mendes RE, Sader HS, Farrell DJ, Critchley IA, Biek D, Le J, Skochko SM, Jones RN and Bradley JS. published in Pediatr. Infect. Dis. J. 2016; 35 (7): 813-815

Oritavancin activity tested against molecularly-characterized staphylococci and enterococci displaying elevated linezolid MIC results.

Oritavancin activity tested against molecularly-characterized staphylococci and enterococci displaying elevated linezolid MIC results. by Mendes RE, Farrell DJ, Sader HS, Flamm RK and Jones RN. published in Antimicrob. Agents. Chemother. 2016; 60 (6): 3817-3820

Performance of BD Max StaphSR for screening of methicillin-resistant Staphylococcus aureus isolates among a contemporary and diverse collection from 146 institutions located in nine U.S. Census Regions: Prevalence of mecA dropout mutants.

Performance of BD Max StaphSR for screening of methicillin-resistant Staphylococcus aureus isolates among a contemporary and diverse collection from 146 institutions located in nine U.S. Census Regions: Prevalence of mecA dropout mutants. by Mendes RE, Watters AA, Rhomberg PR, Farrell DJ and Jones RN. published in J. Clin. Microbiol. 2016; 54 (1): 204-207

Beta-lactamase characterization of Gram-negative pathogens recovered from patients enrolled in the phase 2 trials for ceftazidime-avibactam: Clinical efficacies analyzed against subsets of molecularly characterized isolates.

Beta-Lactamase characterization of Gram-negative pathogens recovered from patients enrolled in the phase 2 trials for ceftazidime-avibactam: Clinical efficacies analyzed against subsets of molecularly characterized isolates. by Mendes RE, Castanheira M, Gasink L, Stone GG, Nichols WW, Flamm RK and Jones RN. published in Antimicrob. Agents. Chemother. 2015; 60 (3): 1328-1335