Publications

Epidemiology and Susceptibility Profiles of ST131-025b Escherichia coli Detected Among Cephalosporin- and/or Carbapenem-Resistant Isolates Collected in United States Hospitals. Lead author: M Castanheira presented at IDWeek 2021, September 29-October 3, Virtual Conference

Occurrence of β-Lactamases among Enterobacterales Isolated from United States Hospitals: Results of the INFORM Surveillance Program for Ceftazidime-Avibactam. Lead author: M Castanheira presented at IDWeek 2021, September 29-October 3, Virtual Conference

In Vitro Analysis of AmpC β-lactamase Induction by Tebipenem in Enterobacterales and Pseudomonas aeruginosa. Lead author: RE Mendes presented at IDWeek 2021, September 29-October 3, Virtual Conference

Optimization of a 96-Well Plate Format Assay to Evaluate Concentration-Dependent Activity of a Monoclonal Antibody against the O Antigen 025b from ST131-H30 Escherichia coli. Lead author: J Lindley presented at IDWeek 2021, September 29-October 3, Virtual Conference

In vitro Activity of Tebipenem, an Orally Available Carbapenem Agent, against a Collection of Surveillance Gram-positive Clinical Isolates. Lead author: SJR Arends presented at IDWeek 2021, September 29-October 3, Virtual Conference

Analysis of Resistance to Oral Standard of Care Antibiotics for Urinary Tract Infections Caused by Escherichia coli and Staphylococcus saprophyticus Collected Worldwide between 2019-2020. Lead author: SJR Arends presented at IDWeek 2021, September 29-October 3, Virtual Conference

Update on the In Vitro Activity of Ceftaroline against Staphylococcus aureus from United States (US) Medical Centers Stratified by Infection Type (2018-2020). Lead author: HS Sader presented at IDWeek 2021, September 29-October 3, Virtual Conference

Molecular Epidemiology of Escherichia coli Causing Urinary Tract Infections in United States and In Vitro Activity of Tebipenem, Including against Strain Lineage and Resistant Subsets (2018-2020). Lead author: RE Mendes presented at IDWeek 2021, September 29-October 3, Virtual Conference

Antimicrobial Activity of Plazomicin against Multidrug-resistant Enterobacterales: Results from 3 Years of Surveillance in Hospitals in the United States (2018-2020). Lead author: HS Sader presented at IDWeek 2021, September 29-Ocrtober 3, Virtual Conference

Oritavancin Activity Against Methicillin-Resistant S. aureus (MRSA) Isolates Causing Skin and Skin Structure Infections in US Hospitals (2017-2019). Lead author: CG Carvalhaes presented at IDWeek 2021, September 29-October 3, Virtual Conference

Minocycline activity against Acinetobacter baumannii-calcoaceticus species complex, Burkholderia cepacia complex, and Stenotrophomonas maltophilia from US hospitals. Lead author: D Shortridge, presented at IDWeek 2021, September 29-October 3, Virtual Conferece

Activity of meropenem/vaborbactam and comparators against Gram-negative isolates from Eastern and Western European patients hospitalized with pneumonia including ventilator-associated pneumonia (2014-19). by Shortridge D, Carvalhaes C, Deshpande L and Castanheira M. published in J Antimicrob Chemother. 2021; 76 (10): 2600-2605

Antimicrobial Susceptibility of Gram-negative Organisms from Southeast Asia. Lead author: H Sader presented at 13th International Symposium on Antimicrobial Agents and Resistance (ISAAR 2021), September 9-10, 2021, Virtual Conference
Poster #0323

Anti-staphylococcal lysin, LSVT-1701, activity: In vitro susceptibility of Staphylococcus aureus and coagulase-negative staphylococci (CoNS) clinical isolates from around the world collected from 2002 to 2019. by Huang DB, Sader HS, Rhomberg PR, Gaukel E and Borroto-Esoda K. published in Diagn. Microbiol. Infect. Dis. 2021; 101 (3): 115471

Antifungal drugs work together to treat germs causing fungal infections. by Pfaller MA, Messer SA, Deshpande LM, Rhomberg PR, Utt EA and Castanheira M. published in Future Microbiol. 2021; 16: 765-768

Intermethod Comparability Analyses of Gepotidacin Antimicrobial Susceptibility Tests Using Over 3,600 Globally-collected Clinical Isolates. Lead author: SJR Arends presented at World Microbe Forum, 20-24 June 2021, Virtual Conference

Current Epidemiology and Activity of Gepotidacin and Comparator Agents Against Escherichia coli Surveillance Isolates Causing Urinary Tract Infections in the Unites States. Lead author: RE Mendes presented at World Microbe Forum, 20-24 June 2021, Virtual Conference

Extended-spectrum beta-lactamases: An update on their characteristics, epidemiology and detection. by Castanheira M, Simner PJ and Bradford PA publised in JAC Antimicrob. Resist. 2021; 3 (3): dlab092

In Vitro Evaluation of Delafloxacin Activity when Tested against Contemporary Isolates from European Acute Skin and Skin Structure Infections: Results from the SENTRY Antimicrobial Surveillance Program (2018-2020). Lead author: D Shortridge presented at ECCMID 2021, July 9-12, Virtual Conference
Poster # 1529

Comparative activity of posaconazole and systemic azole agents against clinical isolates of filamentous fungi from a global surveillance programme. by Carvalhaes CG, Rhomberg PR, Pfaller M and Castanheira M. published in JAC Antimicrob. Resist. 2021; 3 (2): dlab088

Frequency of Occurrence and Antimicrobial Susceptibility of Bacteria Isolated from Patients Hospitalised with Bacterial Pneumonia in Western Europe and Eastern Europe: Results from the SENTRY Program (2018-2020). Lead author: H Sader presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #718

Activity of Cefiderocol and Comparators against European Enterobacterales Including Carbapemen-Resistant Isolates. Lead author: D Shortridge presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #1563

In Vitro Post-Antifungal Effect of Amphotericin B, Fluconazole, and Micafungin against Candida albicans, Candida glabrata, and Candida parapsilosis. Lead author CG Carvalhaes, presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #1630

Azole Resistance In Candida glabrata Clinical Isolates from Global Surveillance Is Associated with Efflux Overexpression. Lead author: L Deshpande presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #02265

Antimicrobial Activities of Cefepime, Meropenem, Aztreonam, and Piperacillin Combined with Nacubactam against Molecularly Characterized Enterobacterales Collected Worldwide. Lead author: HS Sader presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #893

Activity of Meropenem-Vaborbactam and Comparators against European Carbapenem-Resistant Enterobacterales Isolates without a Carbapenemase. Lead author: D Shortridge presented at ECCMID 2021, July 9-12, Virtual Conference
Poster # 1047

Activity of Cefiderocol and Comparators against US Enterobacterales, Including Carbapenem-Resistant Isolates. Lead author: D Shortridge presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #1591

Activity of Meropenem-Vaborbactam and Comparators against Pseudomonas aeruginosa Isolates from Patients with Pneumonia in European Hospitals. Lead author: D Shortridge presented at ECCMID 2021, July 9-12, Virtual Conference
Poster # 1048

Epidemiology and Molecular Characterization of Linezolid Non-Susceptible Enterococcus spp. Clinical Isolates from the SENTRY Antimicrobial Surveillance Program (2017-2019). Lead author: CG Carvalhaes presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #051

In Vitro Activity of Gepotidacin and Comparators Against a Collection of E. coli and S. saprophyticus Urine Isolates Collected from Europe during 2019-2020. Lead author: SJR Arends, presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #2122

High Prevalence of Tetracycline Resistance Genes among Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis Clinical Isolates Causing Infections in Europe (2019). Lead author L Deshpande presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #2235

Five Years of Analysis of the In Vitro Activity of Tedizolid against a Worldwide Collection of Indicated Species Causing Clinical Infections: Results from the Surveillance of Tedizolid Activity and Resistance (STAR) Program. Lead author: CG Carvalhaes presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #264

Prevalence of CC131 and the Emergence of Other Sequence Types among Escherichia coli Isolates Causing Urinary Tract Infections from Asia-Pacific, Europe, and Latin America. Lead author: LM Deshpande presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #422

Oritavancin Activity against Gram-Positive Pathogens causing Bone and Joint Infections In European Medical Centres (2015-2019). Lead author: CG Carvalhaes presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #1626

Evaluation of Pleuromutilins Resistance Mechanisms Among Surveillance Clinical Isolates: Results from the Worldwide Surveillance Program for Lefamulin in 2019. Lead author: RE Mendes, presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #2146

Activity of KBP-7072, a Novel Aminomethylcycline Antibacterial, and Tetracycline Class Comparators Against 1,057 Bacterial Pathogens Collected Worldwide During 2019. Lead author: M Huband presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #1510

In Vitro Activity of a Novel Aminomethylcycline Antibacterial (KBP-7072) against Clinical Isolates with Molecularly Characterized Tetracycline Resistance Mechanisms. Lead author: RE Mendes presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #2189

Activity of Oritavancin and Comparators against a Contemporary Collection of Enterococcus spp. Clinical Isolates from Europe (2015-2019). Lead author: CG Carvalhaes presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #1616

Assessment of Resistance Development to KBP-7072 by Serial-Passage and Single-Step Mutational Selection. Lead author: MD Huband presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #1499

Antimicrobial Activities of Aztreonam-Avibactam and Comparator Agents Tested against Enterobacterales from European Hospitals Analysed by Infection Type (2019-2020). Lead author: H Sader presented at ECCMID 2021, July 9-12, Virtual Conference
Poster # 722

Activity of Cefiderocol and Comparators against US Isolates of Pseudomonas aeruginosa, Acinetobacter baumannii-calcoaceticus species complex, and Stenotrophomonas maltophilia, Including Carbapenem-Resistant Isolates. Lead author: D Shortridge presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #1606

Evaluation of a Protocol for Scalable Preparation of Broth Microdilution Panels for Antifungal Susceptibility Testing Using the EUCAST Reference Method. Lead author: PR Rhomberg presented at ECCMID 2021, July 9-12, Virtual Conference
Poster #877

Antifungal susceptibilities of opportunistic filamentous fungal pathogens from the Asia and Western Pacific Region: Data from the SENTRY Antifungal Surveillance Program (2011-2019). by Pfaller MA, Carvalhaes CG, Rhomberg P, Messer SA and Castanheira M published in J. Antibiot. (Tokyo). 2021; 74 (8): 519-527

Antimicrobial activity of manogepix, a first-in-class antifungal, and comparator agents tested against contemporary invasive fungal isolates from an international surveillance program (2018-2019). by Pfaller MA, Huband MD, Flamm RK, Bien PA and Castanheira M. published in J. Glob. Antimicrob. Resist. 2021; 26: 117-127

Activity of plazomicin against carbapenem-intermediate or -resistant Escherichia coli isolates from the United States and international sites in relation to clonal background, resistance genes, co-resistance, and region. by Johnston BD, Thuras P, Porter SB, Anacker M, VonBank B, Snippes Vagnone P, Witwer M, Castanheira M and Johnson JR. J. Antimicrob. Chemother.: in press, 2021.

Isavuconazole nonwildtype Aspergillus fumigatus isolates from a global surveillance study display alterations in multiple genes involved in the ergosterol biosynthesis pathway not previously associated with resistance to other azoles. by Castanheira M, Collingsworth TD, Davis AP, Deshpande LM and Pfaller MA. published in Mycoses. in press, 2021.

Characterization of a vga gene variant recovered from a Staphylococcus saprophyticus causing a community-acquired urinary tract infection: Report from the SENTRY Antimicrobial Surveillance Program 2017. by Deshpande L, Cantrell L, Romero JR, Carvalhaes C and Sader HS. published in Diagn. Microbiol. Infect. Dis. 2021; 100 (4): 115398

Tedizolid activity against a multicentre worldwide collection of Staphylococcus aureus and Streptococcus pneumoniae recovered from patients with pneumonia (2017-2019). by Carvalhaes CG, Sader HS, Rhomberg PR and Mendes RE. published in Int. J. Infect. Dis. 2021; 107: 92-100

Evaluation of synergistic activity of isavuconazole or voriconazole plus anidulafungin and the occurrence and genetic characterization of Candida auris detected in a surveillance program. by Pfaller MA, Messer SA, Deshpande LM, Rhomberg PR, Utt EA and Castanheira M. published in Antimicrob. Agents Chemother. 2021; 65 (4): e02031

Molecular characterization of baseline Enterobacterales and Pseudomonas aeruginosa isolates from a Phase 3 nosocomial pneumonia (ASPECT-NP) clinical trial. by Castanheira M, Johnson MG, Yu B, Huntington JA, Carmelitano P, Bruno C, Rhee EG and Motyl M. published in Antimicrob. Agents Chemother. 2021; 65 (3): e02461