Filter by Category: Molecular Studies

Efficacy of Omadacycline against Molecularly Characterized Gram-Positive and Gram-Negative Pathogens Causing Infections in the Phase 3 CABP and ABSSSI Clinical Trials.

Efficacy of Omadacycline against Molecularly Characterized Gram-Positive and Gram-Negative Pathogens Causing Infections in the Phase 3 CABP and ABSSSI Clinical Trials. Lead author: RE Mendes, presented at IDWeek 2018, October 3-7, San Francisco, CA, USA
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Omadacycline In Vitro Activity against a Molecularly Characterized Collection of Clinical Isolates with Known Tetracycline Resistance Mechanisms.

Omadacycline In Vitro Activity against a Molecularly Characterized Collection of Clinical Isolates with Known Tetracycline Resistance Mechanisms. Lead author: RE Mendes, presented at IDWeek 2018, October 3-7, San Francisco, CA, USA
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Disruption of mgrB and Alterations on pmrB Are Most Common Resistance Mechanisms among Colistin-Resistance among Klebsiella pneumoniae from a Global Surveillance Program

Disruption of mgrB and Alterations on pmrB Are Most Common Resistance Mechanisms among Colistin-Resistance among Klebsiella pneumoniae from a Global Surveillance Program. Lead author: M Castanheira, presented at ASM Microbe 2018, June 7-11, Atlanta, GA, USA
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Molecular Characterization of Clinical Trial Isolates Exhibiting Increased MIC Results during Fosfomycin (ZTI-01) Treatment in a Phase 2/3 Clinical Trial for Complicated Urinary Tract Infections (ZEUS)

Molecular Characterization of Clinical Trial Isolates Exhibiting Increased MIC Results during Fosfomycin (ZTI-01) Treatment in a Phase 2/3 Clinical Trial for Complicated Urinary Tract Infections (ZEUS). Lead author: RE Mendes, presented at ASM Microbe 2018, June 7-11, Atlanta, GA, USA
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Distribution of β-Lactamase Resistance Genes and Lineage Background in Clinical Isolates Producing Extended-Spectrum β-Lactamases by High-Resolution Genomic Analysis

Distribution of β-Lactamase Resistance Genes and Lineage Background in Clinical Isolates Producing Extended-Spectrum β-Lactamases by High-Resolution Genomic Analysis. Lead author: RE Mendes, presented at ASM Microbe 2018, June 7-11, Atlanta, GA, USA
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Correlation between Broth Microdilution and Disk Diffusion Methods Results When Testing Ceftaroline against Methicillin-Resistant Staphylococcus aureus and Molecular Characterization of Isolates with Elevated Ceftaroline MIC Results

Correlation between Broth Microdilution and Disk Diffusion Methods Results When Testing Ceftaroline against Methicillin-Resistant Staphylococcus aureus and Molecular Characterization of Isolates with Elevated Ceftaroline MIC Results. Lead author: HS Sader, presented at ASM Microbe 2018, June 7-11, Atlanta, GA, USA
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Molecular Characterization of Resistance Mechanisms Associated with Pleuromutilins Among Gram-Positive Clinical Isolates From the Worldwide SENTRY Surveillance Studies for Lefamulin

Molecular Characterization of Resistance Mechanisms Associated with Pleuromutilins Among Gram-Positive Clinical Isolates From the Worldwide SENTRY Surveillance Studies for Lefamulin. Lead author: RE Mendes, presented at ASM Microbe 2018, June 7-11, Atlanta, GA, USA
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Molecular beta-lactamase characterization of gram-negative pathogens recovered from patients enrolled in the ceftazidime-avibactam phase 3 trials (RECAPTURE 1 and 2) for complicated urinary tract infections: Efficacies analysed against susceptible and resistant subsets.

Molecular beta-lactamase characterization of gram-negative pathogens recovered from patients enrolled in the ceftazidime-avibactam phase 3 trials (RECAPTURE 1 and 2) for complicated urinary tract infections: Efficacies analysed against susceptible and resistant subsets. by Mendes RE, Castanheira M, Woosley LN, Stone GG, Bradford PA and Flamm RK published in Int. J. Antimicrob. Agents. 2018; 52 (2) 287-292

Evaluation of synergistic effects of a potentiator molecule (SPR741) when tested in combination with a series of β-lactam agents against a challenge set of Gram-negative pathogens.

Evaluation of synergistic effects of a potentiator molecule (SPR741) when tested in combination with a series of β-lactam agents against a challenge set of Gram-negative pathogens. Lead author: RE Mendes, presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2018, April 21-24, Madrid, Spain
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Case report of transient mcr-1-haboring Escherichia coli with concurrent Staphylococcus aureus bacteremia in Long Beach, California.

Case report of transient mcr-1-haboring Escherichia coli with concurrent Staphylococcus aureus bacteremia in Long Beach, California. by Le J, Turner N, Deshpande LM, Davis AP and Castanheira M published in Diagn. Microbiol. Infect. Dis. 2017; 89 (4): 303-304